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A Palestine woman and two children were killed and an infant was injured when the car they were in went off the road and hit a tree.

The Texas Department of Public Safety responded to the crash at 4:17 p.m. Tuesday about 6 miles north of Palestine in Anderson County, according to a news release from the department.

The DPS said the preliminary crash investigation showed Ruby Kwame, 34, was driving south on U.S. Highway 287 in a 2005 Camry when the car veered from the southbound lane into the northbound lane, went into the north ditch and struck a trash bin and a tree.

Kwame was pronounced dead at the scene, according to the DPS.

The DPS said a 4-year-old boy and a 2-year-old boy were taken to Palestine Regional Medical Center, where they later died.

An 8-month-old girl was taken to Palestine Regional Medical Center in stable condition, according to the department.

The DPS said the initial report indicates all in the car were restrained.

The crash remains under investigation.