Remarks are set for 11 a.m. in the main lobby of the health science center, 11937 U.S. Highway 271.
Mayor Barbara Bass and hospital President Dr. Kirk Calhoun are expected to share details about the new educational venture.
The March annexation was initiated by the hospital, officials said.
The hospital’s campus is 593.11 acres.
As a result of the annexation, Tyler’s boundaries encompass 57.02 square miles of 36,494.90 acres.
“We are pleased to see this process move forward,” Calhoun said, also in a statement. “We look forward to becoming a part of Tyler not only in name, but as a partner in our city’s future growth and development.”
Adjacent properties remain unaffected by the annexation, city officials said.